Here members can share stories, find important information and learn from the experiences of others like themselves. [7] Kinoshita S, Sone S, Yamashita T, Tsubura E, Ogura T: Effects of experimental hyperand hypothyroidism on natural defense activities against Lewis lung carcinoma and its spontaneous pulmonary metastases in C57BL/6 mice. It looks at correlations, as if they had any merit on their own. SayerJiis founder ofGreenmedinfo.com, a reviewer at theInternational Journal of Human Nutrition and Functional Medicine,Co-founder and CEO of Systome Biomed, Vice Chairman of the Board of theNational Health Federation, SteeringCommittee Memberof the Global Non-GMO Foundation. You may not notice signs or symptoms of the disease. Endocrinol. Sub-laboratory hypothyroidism and the empirical use of Armour thyroid. By rejecting non-essential cookies, Reddit may still use certain cookies to ensure the proper functionality of our platform. I have so many women friends and family members who have recently been diagnosed with hypothyroidism and their doctors put them all on Synthyroid. It's possible, for instance, that the reason both sales of Synthroid and the incidence of lung cancer increased is due to an environmental condition that affected both the thyroid and the lungs. Curr Opin Endocrinol Diabetes Obes 2010, 17:432436. If You Don't Want Older Bones, Don't Be Low In Vit Background Mortality Rate for Vaccines, or Pseudo Everything You Ever Wanted to Know About Black Seeds. 1). In an attempt to show causation, the article notes "patients with small cell carcinoma of the lung often present symptoms suggestive of hyperthyroidism (i.e. ', Study: Millions Treated for Hypothyroidism At Risk for Lung Cancer. PLoSone 2011, 11:e27547. Whereas a patient who had suboptimal thyroid function, but did not have noticeable symptoms, is suddenly given pharmacological doses of synthetic T4 and suddenly experiences the wide range of acute, adverse health effects associated with a now hyperactive and/or increasingly disrupted thyroid, as a result. Log In. Oops I have just bought my first jar of marmalade in over ten years! Biomedicine today is awash in controversy associated with the overdiagnosis and overtreatment of asymptomatic populations. Other research indicating that increased thyroid activity (hyperthyroidism) contributes to lung cancer pathogenesis was presented, including: The authors also cite animal experimental research which has shown that T4 increases the oxidative stress[6] and spontaneous pulmonary metastases in mice. This is a news report of the research, so I can't learn the details of how the science was conducted. However, I do not believe it was out of the blue now. Diagnosed 1/12 with lung cancer out of the blue. "Serum TSH, T(4), and thyroid antibodies in the United States population (1988 to 1994): National Health and Nutrition Examination Survey (NHANES III)", International Journal of Human Nutrition and Functional Medicine, Osteoporosis Is Scurvy of the Bone, Not Calcium Deficiency, 6 Bodily Tissues That Can Be Regenerated Through Nutrition, 7 Simple Ways to Unclog Your Arteries Naturally, Herbal Cream Clears 87.7% of HPV Cases Naturally, How WHOLE Turmeric Heals the Damaged Brain. In the United States, autoimmune thyroid disease (Hashimoto thyroiditis) is the most common cause of hypothyroidism, but globally lack of iodine in the diet is the most common cause. I was sure that the paper had been discussed here shortly after publication in 2013, but cannot find the thread! I can understand why tennis 123 wrote, "I have so much to say about this I could write a book". Assessment of oxidative stress and its balance has not been taken into consideration up to now as it should be. Why not simply call it selenium deficiency? J Exp Biol 2010, 213:28992911. A new study has uncovered a link between the synthetic thyroid hormone (trade name Synthroid) used to treat millions diagnosed with hypothyroidism and lung cancer, bringing to the forefront the harmful role that overdiagnosis and overtreatment plays in nutritional deficiency and chemical exposure related 'diseases.'. Just go on one of the thyroid sites and read the stories. Comp Biochem Physiol C Toxicol Pharmacol 2002, 133:475481. El almacenamiento o acceso tcnico es necesario para la finalidad legtima de almacenar preferencias no solicitadas por el abonado o usuario. This article is copyrighted by GreenMedInfo LLC, 2013, Some features are currently member only features. In my opinion, the science of the study doesn't support the conclusion. 2004 Jun;9(2):157-79. J Endocrinol Invest. The increasingly global medical-industrial complex has begun to co-opt all aspects of the natural human bodily life cycle, and all the organ systems within it, as potential targets of medical surveillance and intervention, not excluding the human thyroid. The authors of the study pointed out that levothyroxine (T4) treatment can lead to medication-induced (iatrogenic) thyroid over-activity (hyperthyroidism) and oxidative stress that can lead to a significant patient discomfort. Biomedicine today is awash in controversy associated with the overdiagnosis and overtreatment of asymptomatic populations. Respiratory system Hypothyroidism weakens the respiratory muscles and decreases lung function. [13] Hollowell JG, Staehling NW, Flanders WD. Millions of people who were not only wrongly diagnosed with cancers and subsequently aggressively treated for them with chemotherapy, radiation and surgery, are now being told that they would have been better left undiagnosed and untreated. Non-small cell lung cancer is the most common type of lung cancer, accounting for about 81% of all cases. The Goji Berry: The Jolly Super Food That Gives Yo How to Prevent and Treat Insect Bites Without Hars Supreme Court Rules Drug Companies Exempt From Law Spain Study Confirms Hemp Oil Cures Cancer without Wheatgrass Turns Gray Hair Back to Its Natural Color, Medicinal Cannabis Used To Prevent Cancer Growth. Capmatinib (Tabrecta) is the first FDA-approved MET-targeting medication for treating metastatic NSCLC. In comparison, 62.4% of female and 37% of male . Comp Biochem Physiol C Toxicol Pharmacol 2002, 133:475481. elevated TSH, without actually improving the overall physiological situation, nor the patient's subjective experience of well being. Finally, they pointed out that T4, which is a synthetic form of thyroid hormone, might be avoided if T3 or the desiccated pig-derived form known as Armour Thyroid was used to control the oxidative-stress producing hydroperoxides. 2 Hypothyroidism is the most common type of thyroid disorder, and women's risk of hypothyroidism is five to eight times higher than that of . PMID: 23539727, [16] Alan R Gaby. [9] Otto T, Fandrey J: Thyroid hormone induces hypoxia-inducible factor 1 gene expression through thyroid hormone receptor /retinoid x receptor -dependent activation of hepatic leukemia factor. I'm not saying that there Is no link between Synthroid and lung cancer. 'A new Italian study published in the journal Reproductive Biology and Endocrinology titled, "Levothyroxine and lung cancer in females: the importance of oxidative stress," has raised a concerning possibility: levothyroxine (T4), one of the world's most commonly prescribed forms of hormone replacement, may be raising the risk of lung cancer in millions of men and women being treated for low . weight loss, anorexia). " Even acute bouts of stress and subclinical adrenal insufficiency can cause cyclical downshifts in thyroid function. I have so much to say about this I could write a book. Medical Authoritys System Kills: FDA-Approved Dru Cognitive Impairment, Memory Loss and Alzheimer's Soy Lecithin: How It Negatively Affects Your Healt Cannabis Oil Cures Cancer -Lincoln Horsley's Story New Information Dissolves Illusions About Vaccines Grounding Helps Thin Dangerously Thick Blood and F Tart Cherries Relieve Osteoarthritis Pain, Lieberman's Massive Connections To Big Pharma, Utopian 'Harvest Your Own' Groceries Coming Up. This relatively symptom-free reservoir of hypothyroid cases provides a veritable gold mine of potential office visits, billable services and drug prescriptions. An Italian study published in the journalReproductive Biology and Endocrinology,titled Levothyroxine and lung cancer in females: the importance of oxidative stress, has raised a concerning possibility: levothyroxine (T4), one of the worlds most commonly prescribed forms of hormone replacement, may be raising the risk of lung cancer in millions of men and women being treated for low thyroid function (hypothyroidism). Metab.87 (2): 48999. [4] Ratcliffe JG, Stack BH, Burt RW, Radcliffe WA, Spilg WG, Cuthbert J, Kennedy RS: Thyroid function in lung cancer. Sayer Ji is the founder ofGreenmedinfo.com, a reviewer at theInternational Journal of Human Nutrition and Functional Medicine,Co-founder and CEO of Systome Biomed, Vice Chairman of the Board of theNational Health Federation, and SteeringCommittee Memberof the Global Non-GMO Foundation. By accepting all cookies, you agree to our use of cookies to deliver and maintain our services and site, improve the quality of Reddit, personalize Reddit content and advertising, and measure the effectiveness of advertising. I have sent the link that I read today. Even acute bouts of stress and subclinical adrenal insufficiency can cause cyclical downshifts in thyroid function. [11] Wan J, Chai H, Yu Z, Ge W, Kang N, Xia W, Che Y: H1F-1 on angiogenic potential in human small cell carcinoma. This is a horrible disease that ravages the body. Why not simply call it selenium deficiency? For a better experience, please enable JavaScript in your browser before proceeding. Sin un requerimiento, el cumplimiento voluntario por parte de tu Proveedor de servicios de Internet, o los registros adicionales de un tercero, la informacin almacenada o recuperada slo para este propsito no se puede utilizar para identificarte. A new study has uncovered a link between the synthetic thyroid hormone (trade name Synthroid) used to treat millions diagnosed with hypothyroidism and lung cancer, bringing to the forefront the harmful role that overdiagnosis and overtreatment plays in nutritional deficiency and chemical exposure related 'diseases.' The article also stresses that too many people are being given the diagnosis of either hypo or hyperthyroidism. The study looked at the prevalence of breast, colorectal, gastric and lung cancer in 18 Italian Regions during 2010 and correlated this data with sales of LT4 in 2009, focusing on women aged 30-84. [3] Faber J, Poulsen S, Iversen P, Kirkegaard C: Thyroid hormone turnover in patients with small cell carcinoma of the lung. [10] Hofer T, Desbaillets I, Hpfl G, Wenger RH, Gassmann M: Characterization of HIFD-1 alpha overexpressing Hela cells and implication for gene therapy. Garlic Beats Drug in Detoxifying Lead Safely From How Yoga and Acupuncture Enhance HealthNew Resear Health Nuts: Seeds And Nuts You Should Eat Every Day. weight loss, anorexia) was made many years ago together with an over production of both T4 and T3. Thyroid disease is a major public health concern worldwide. Those with the greatest risk of developing thyroid disorders are women who have a family history of the disease. and our In fact, a 2004 study in subjects with normal thyroid function found that administration of tyrosine leads to a significant reduction in serum TSH and improvement in mood in winter compared with placebo, while the combined synthetic T4-T3 supplement leads to a worsening of mood in summer and no improvement in winter, indicating supporting glandular function is superior to 'replacement' therapy, as well as the role seasonality may play in hormone function and hormone treatment interventions. The authors delved deeper into the reason why oxidative stress taking place during T4 treatment is particularly linked to lung cancer only: The hypothesis could be that in lungs the increase of hypoxia-induced factor (HIF-1) which is determined by T4 can make oxygen much more available, increasing locally the oxidative stress together with a dangerous angiogenesis stimulation. The increasingly global medical-industrial complex has begun to co-opt all aspects of the natural human bodily life cycle, and all the organ systems within it, as potential targets of medical surveillance and intervention, not excluding the human thyroid. Oops, I just saw that I posted the same article. ", Cure Alveolar Soft Part Sarcoma International, COMPLETED - Dana Farber Vaccine Clinical Trial (GVAX), Axitinib and Pembrolizumab (Keytruda) in Miami, US, TECENTRIQ (atezolizumab) by Genentech, Treatment of Non-Resectable Primary Tumor, Immune checkpoint inhibitors ICI (PD-1 and PD-L1 targeting drugs), Toxicity, problems and potentiation strategies, Treatment response criteria and evaluation/scanning problems/rare cases, treatment discontinuation/re-treatment, Side effects/complications of the local ablations, High intensity focused ultrasound (HIFU), Study: Millions Treated for Hypothyroidism At Risk for Lung Cancer, http://www.greenmedinfo.com/blog/study- ng-cancers. Furthermore, the geometric expansion of hypothyroidism cases in the past decade only thinly conceals an agenda to promote the synthetic form of T4 known as levothyroxine sodium (trade name Synthroid), since with each new 'disease' case the patient is converted into a lifelong customer. Nope. Endocrinology 1985, 117:12011208. [11] Wan J, Chai H, Yu Z, Ge W, Kang N, Xia W, Che Y: H1F-1 on angiogenic potential in human small cell carcinoma. This website is for information purposes only. Untreated hypothyroidism increases morbidity and mortality. J Exp Biol 2010, 213:28992911. [2] Meng R, Tang HY, Westfall J, London D, Cao JH, Mousa SA, Luidens M, Hercbergs A, Davis FB, Davis PJ, et al: Crosstalk between integrin v3 and estrogen receptor- is involved in thyroid hormone-induced proliferation in human lung carcinoma cells. I honestly do not know. Physician/Author on Facebook. They also noted that oxidative stress is one of the causes of chronic diseases and cancer. PMID: 11929079, [15] Thanh D Hoang, Cara H Olsen, Vinh Q Mai, Patrick W Clyde, Mohamed K M Shakir. May be of interest: Study: Millions Treated for Hypothyroidism At Risk for, Non-small cell lung cancer - Adenocarcinoma, Non-small cell lung cancer - Squamous cell, Top 5 Questions to Ask Your Lung Cancer Doctor, Patient & Caregiver Network Member Resources, Not A Member Yet? Maybe because they "treat" only with T4 and not T3? It does not seem to quantify the increased risk, and it keeps saying it is hyperthyroidism that causes the oxidised stress. If people do not wish to find out all they can about their disease that is fine too. [4], DI activity in lung cancer was found to be lower than in peripheral lung tissue.[5]. [1] Hercbergs AH, Ashur-Fabian O, Garfield D: Thyroid hormone and cancer: clinical studies of hypothyroidism in oncology. They found no significant correlation between T4 sales and breast, colorectal and gastriccancers, but did find a significant correlation for lung cancer (p < 0.05) corrected forsmoking and age. Endocrinology 2008, 149:22412250. Other factors that can trigger thyroid problems include: autoimmune diseases like Hashimoto's or Graves' disease; thyroid surgery; radiation treatments to the neck or upper chest; and certain medications, including interferon alpha and interleukin-2 cancer medications, amiodarone . Indeed, research indicates that hypothyroid patients treated with T4 replacement, that is sufficient to maintain a normal serum TSH, actually have serum free T4 that is higher than in untreated normal patients and may not result in appropriately normal serum free T3 concentrations. If you are already a member, please, Levothyroxine and lung cancer in females: the importance of oxidative stress, recent announcement by a National Cancer Institute, T-score based definition of osteoporosis and osteopenia, 30-billion dollar a year market in statin drugs. With the 2013 announcement by a National Cancer Institutecommissioned expert panel that a variety of so-called indolent neoplasms such as ductal carcinoma in situ(DCIS) and high-grade prostatic intraepithelial neoplasia (HGPIN), formerly understood to be forms of breast and prostate cancers, respectively, should be renamed to reflect their intrinsic benignity, a veritable sea change is occurring within the conventional medical establishment. Hypothyroidism can also lead to swelling of the tongue, hoarse voice, and sleep apnea. When a high-risk patient presents with one or more lung nodules, the path ahead and next steps seems obvious. In 2020 alone, there were more than 2.2 million new cases and 1.8 million deaths from lung cancer globally. The Flu Propaganda Matrix Continues To Promote Fea B Vitamins Slow Alzheimer's and Grey Matter Loss. Overtreatment, of course, is the hallmark danger of overdiagnosis. There are many links attached. I will respond more later onBut I will briefly say I was on Synthyroid from 1993 to 2011. I have posted the link now. For more information, please see our millions treated for hypothyroidism at risk for lung cancer. So I will leave it as a simple thank you for passing this along. El almacenamiento o acceso tcnico es necesario para crear perfiles de usuario para enviar publicidad, o para rastrear al usuario en una web o en varias web con fines de marketing similares. One of the main drawbacks of administering T4 in isolation is the possibility that it will not convert adequately to T3, and will therefore back up causing excessive T4 activity, i.e. El almacenamiento o acceso tcnico que es utilizado exclusivamente con fines estadsticos. In discussing their findings, the authors noted that they could not exclude the possibility that the condition of hypothyroidism could favor the development of lung cancer. Millions of people who were not only wrongly diagnosed with 'cancers' and subsequently aggressively treated for them with chemotherapy, radiation and surgery, are now being told that they would have been better left undiagnosed and untreated. This relatively symptom-free reservoir of 'hypothyroid' cases provides a veritable gold mine of potential office visits, billable services and drug prescriptions. Not what people like me are saying. The reality is that most cases of hypothyroidism today are diagnosed in populations who are experiencing a combination of basic nutritional deficiencies and chemical exposures, or who are simply going through a temporary down-cycle in thyroid function following a natural change, such as the natural postpartum drop that occurs in women after giving birth. When a high-risk patient presents with one or more lung nodules, the path ahead and next steps seems obvious. I am just as much in the dark as some others on this site. What I am personally saying issince I personally have a disease that may kill me, I sure as heck have every right to find out ALL I can about it. I very much appreciate the information you shared. Increased sleepiness. Si as lo deseas puedes revisar el resto de nuestros contenidos para encontrar lo que buscabas o directamente utilizar nuestro buscador. In addition, untreated hypothyroidism is associated with a gradual decline in cognitive function and memory. Subclinical hypothyroidism is defined by an elevated serum thyroid-stimulating hormone (TSH) level along with a normal free thyroxine (T4) level. A couple of caveats to note in this study: The authors found a statistical correlation between the increase in sales of the thyroid medicine Synthroid, and an increase in lung cancer in Italy. I wish I could say that my story was atypical. Thyroid dysfunction after immune checkpoint inhibitor treatment in a single-center Chinese cohort: a retrospective study But what can be done for patients who are at low The Dangers of Tylenol: Is it Time to for the FDA Chile: Psychiatrist Leads Crusade To Legalize Mari 13 Things Sure To Slow Down Your Metabolism. As a person with Graves Disease, I underwent 6 cycles of radio-ablation using i 131 to 'fry' my thyroid gland as surgery was deemed too risky due to the vascularity and size of my gland. [9] [10] [11] Although we should never forget that LT4 is a life-saving thyroid hormone replacement, and that one should not exclude that the pathological reason that leads to the prescription of LT4 could favor the lung cancer development also. The study looked at the prevalence of breast, colorectal, gastric and lung cancer in 18 Italian Regions during 2010 and correlated this data with sales of LT4 in 2009, focusing on women aged 30-84. Endocrinology 2008, 149:22412250. Content on HealthUnlocked does not replace the relationship between you and doctors or other healthcare professionals nor the advice you receive from them. Whereas a patient who had suboptimal thyroid function, but did not have noticeable symptoms, is suddenly given pharmacological doses of synthetic T4 and suddenly experiences the wide range of acute, adverse health effects associated with a now hyperactive and/or increasingly disrupted thyroid, as a result. [2], The observation that patients with small cell carcinoma of the lung often present symptoms suggestive of hyperthyroidism (i.e. http://www.greenmedinfo.com/blog/study-millions-treated-hypothyroidism-risk-l Study: Millions Treated for Hypothyroidism At Risk for Lung Cancer, Iodine Supplementation Support by VWT Team. The authors expanded on their findings further: "However, the impression we get from our experience in epidemiological studies monitoring[12] is that this drug should be prescribed more cautiously. I discovered this article published in Wakeup World. [8] van Doorn J, Roelfsema F, van der Heide D: Concentration of thyroxine and 3,5,3'-triiodotyronine in several rat tissue in vivo: the effect of hypothyroidism. At GreenMedInfo.com, we have indexed plenty of peer-reviewed research on over 30 natural substances, including nutrients and minerals, which may help to resolve low thyroid function, and conversely, over 30 unnatural substances, e.g. Find how some diseases can be healed with alternative medicine, and share your experience with Share your experience, learn from others. Hypothyroidism reduces respiratory drive and can cause obstructive sleep apnea or pleural effusion, while hyperthyroidism increases respiratory drive and can cause dyspnea on exertion. Could be another marmalade how would we know? A distorted idea of human nature is sold when people are treated as "the market. elevated TSH, without actually improving the overall physiological situation, nor the patients subjective experience of well being. I have no further scientific evidence. Clin Cancer Res 2011, 30:77. Compared to patients without hypothyroidism, those with a high TSH level before hospitalization stayed in the hospital 1.2 days longer and had a 49% higher risk of 30-day readmission and a 43% . The omnipresent environmental contaminant perchlorate, an ingredient in jet fuel, is also a primary cause of hypothyroidism, but is almost never tested for by the conventional endocrinologists in their patient evaluations. 1 The number of individuals with thyroid disorders is expected to continue to grow, having reached approximately 750 million globally in 2012. Or, if fluoride, mercury, or any number of xenobiotic chemicals in the environment requiring selenium-dependent glutathione-mediated detoxification is causing the low thyroid, why call chemical poisoning hypothyroidism? Salt, Sugar, Fat: 15 Shocking Facts From the Book Dear Doctor, Do You Really Know What Vaccines Cont Colloidal Gold: Discover the Benefits and Wonders, Scientists Explain Why HPV Vaccines Are Unsafe. Cookie Notice Lung cancer survivors support group and discussion community, http://www.greenmedinfo.com/blog/study-millions-treated-hypothyroidism-risk-lung-cancers?utm_source=www.GreenMedInfo.com&utm_campaign=2189ddd3c1-Greenmedinfo&utm_medium=email&utm_term=0_193c8492fb-2189ddd3c1-87046221. The study included more than 128,000 veterans aged 18 to 26 and found that, just 30.2% of females and 18.7% of males had received HPV vaccination. Currently, the best practical approach is to base treatment decisions on the degree of TSH elevation, thyroid autoimmunity, and associated comorbidities. It is very tormenting (for me anyhow) to not know why I got this disease. The relationship between levothyroxine use and cancer risk is largely underdetermined. END TIME NEWS, A CALL FOR REPENTANCE, YESHUA THE ONLY WAY TO HEAVEN. I posted it to see what anyone had to add. There is also compelling research indicating that desiccated thyroid extract (Armour thyroid) results in superior clinical outcomes versus the synthetic hormone, especially as concerns improved body weight. If I can help someone, fine. Tokushima J Exp Med 1991, 38:2535. "Serum TSH, T(4), and thyroid antibodies in the United States population (1988 to 1994): National Health and Nutrition Examination Survey (NHANES III)". [1] Hercbergs AH, Ashur-Fabian O, Garfield D: Thyroid hormone and cancer: clinical studies of hypothyroidism in oncology. Correlation is NOT causation. (31) 3351-3382 | 3351-3272 | 3351-3141 | 3351-3371. location of blind frog ranch associe-se. Or, simply look at what the young-adult,T-score based definition of osteoporosis and osteopeniahas done to convert millions of healthy middle-age and older women into drug-treatable patients, or, what the lipid hypothesis of cardiovascular disease causation has done to create a 30-billion dollar a year market in statin drugs, to fully appreciate the harms of overdiagnosis and overtreatment. Non-ASPS articles which could be relevant. [4], More recently DI activity in lung cancer was found to be lower than in peripheral lung tissue.[5]. Heart problems. 2002 Feb ;25(2):106-9. El almacenamiento o acceso tcnico es estrictamente necesario para el propsito legtimo de permitir el uso de un servicio especfico explcitamente solicitado por el abonado o usuario, o con el nico propsito de llevar a cabo la transmisin de una comunicacin a travs de una red de comunicaciones electrnicas.