A controlled trial of a dissolving oral patch concerning glycyrrhiza (licorice) herbal extract for the treatment of aphthous ulcers. View abstract. Gupta D, Agrawal S, Sharma JP. Taking peony along with estrogen might increase the effects and side effects from estrogen. Paeoniae Radix-containing herbal medicine for patients with restless legs syndrome: A systematic review and meta-analysis. Licorice, tobacco chewing, and hypertension. Zhong Xi Yi Jie He Za Zhi 1990;10:101-2, 70. . 17. Black licorice can have serious side effects when eaten in large amounts. Potentiation of hydrocortisone activity in skin by glycyrrhetinic acid. Horm.Res 1999;52(5):253-255. View abstract. View abstract. 2013 Jun;22(2):173-8. Zhou Y, Jin L, Kong F, et al. Kang, D. G., Moon, M. K., Choi, D. H., Lee, J. K., Kwon, T. O., and Lee, H. S. Vasodilatory and anti-inflammatory effects of the 1,2,3,4,6-penta-O-galloyl-beta-D-glucose (PGG) via a nitric oxide-cGMP pathway. Biomed.Chromatogr. Takahara T, Watanabe A, Shiraki K. Effects of glycyrrhizin on hepatitis B surface antigen: a biochemical and morphological study. Clinical trial of deglydyrrhizinized liquorice in gastric ulcer. Petramfar P, Hajari F, Yousefi G, Azadi S, Hamedi A. Efficacy of oral administration of licorice as an adjunct therapy on improving the symptoms of patients with Parkinson's disease, A randomized double blinded clinical trial. Fitoterapia 2004;75:45-9.. View abstract. View abstract. Feng Z, Xu J, He G, et al. Apparent mineralcorticoid excess syndrome, an often forgotten or unrecognized cause of hypokalemia and hypertension: case report and appraisal of the pathophysiology. View abstract. Au, T. K., Lam, T. L., Ng, T. B., Fong, W. P., and Wan, D. C. A comparison of HIV-1 integrase inhibition by aqueous and methanol extracts of Chinese medicinal herbs. Clin Ther 1999;21(12):2080-2090. Cai Y, Yuan Q, Xu K, et al. View abstract. J Cancer Res Ther. Am J Clin Dermatol 2010;11(4):247-267. Heidemann HT, Kreuzfelder E. Hypokalemic rhabdomyolysis with myoglobinuria due to licorice ingestion and diuretic treatment. Front Psychiatry 2020;11:605949. A dual investigation of the effect of dietary supplementation with licorice flavonoid oil on anthropometric and biochemical markers or health and adiposity. Side-effects of low-potassium levels can include lethargy and abnormal heart rhythms. View abstract. View abstract. View abstract. Abe Y, Ueda T, Kato T, Kohli Y. 2020;2020:3727682. Morris DJ, Davis E, Latif SA. Int J Dermatol 1999;38:387-92 . View abstract. View abstract. View abstract. After lab testing, the Cheng team found that Huang Qin Tang had a high inhibitory property against the debilitating side effects of a chemotherapy drug called CPT-11 (later approved as irinotecan), including diarrhea, nausea, and vomiting. Neth J Med 2005;63:146-8. View abstract. View abstract. Panduranga P, Al-Rawahi N. Licorice-induced severe hypokalemia with recurrent torsade de pointes. Lancet 1992;340:13-17. Nutrition 2002;18(3):268-273. mentioned adverse effects and recurrence rates. Imtiaz, K. E. Sweet root, bitter pill: liquorice-induced hyperaldosteronism. 2020. J Peripher.Nerv.Syst. 1991;4(2):166-173. View abstract. Nephrologie 1993;14(4):177-181. Anon. View abstract. View abstract. View abstract. A pilot study. Biol.Pharm Bull. Messier, C., Epifano, F., Genovese, S., and Grenier, D. Licorice and its potential beneficial effects in common oro-dental diseases. Total glucosides of peony ameliorates Sjogren's syndrome by affecting Th1/Th2 cytokine balance. View abstract. Mattarello MJ, Karbowiak I, Ermolao A, and et al. A randomized, double-blind comparison of licorice versus sugar-water gargle for prevention of postoperative sore throat and postextubation coughing. Clin Exp Obstet Gynecol 2013;40(1):141-143. This could change the effects and side effects of these medications. Teelucksingh S, Mackie AD, Burt D, McIntyre MA, Brett L, Edwards CR. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you. We currently have no information for PEONY overview. View abstract. View abstract. Comparative study of bioactive constituents in crude and processed Glycyrrhizae radix and their respective metabolic profiles in gastrointestinal tract in vitro by HPLC-DAD and HPLC-ESI/MS analyses. Exp Neurol 1997;146:518-25. 1993;13(10):591-3, 579. Martin, M. D., Sherman, J., van der Ven, V., and Burgess, J. [13] A study in Japan compared the use of a . Licorice has anti-acid and relieves the tension of gastrointestinal smooth muscle. Corse, F. M., Galgani, S., Gasparini, C., Giacanelli, M., and Piazza, G. Acute hypokalemic myopathy due to chronic licorice ingestion: report of a case. Growth-inhibiting, bactericidal, and urease inhibitory effects of Paeonia lactiflora root constituents and related compounds on antibiotic-susceptible and -resistant strains of Helicobacter pylori. View abstract. View abstract. Licorice root is aromatic and is used as a flavoring agent in tea and other beverages. This information may not fit your specific health circumstances. 2020;50:102401. About Dr.Cope. Planta Med 2003;69(12):1113-1118. Fang, J. Y. Dellow EL, Unwin RJ, Honour JW. Digestion 2004;69:45-52. View abstract. Guo, D., Ye, G., and Guo, H. A new phenolic glycoside from Paeonia lactiflora. View abstract. 2000;20(1):38-41. Also for White Peony, the plant that is used in traditional . Nihon Jinzo Gakkai Shi 2010;52(1):80-85. Licorice might change how quickly the liver breaks down these medications. Gut 1973;14(9):711-715. Z Gastroenterol 2001;39(7):511-7. Pontefract cakes can be bad for you: refractory hypertension and liquorice excess. October 15, 2021. Peony might have some of the same effects as estrogen. People who regularly take large amounts of licorice, more than 20 g/day, may raise blood levels of the hormone aldosterone, which can cause serious side effects, including headache, high blood pressure, and heart problems. View abstract. View abstract. Mechanisms by which Hange-shashin-to reduces prostaglandin E2 levels. View abstract. In a 30-day study in 50 adults with indigestion, taking a 75-mg licorice . Cancer Res 2000;60:5704-9.. View abstract. View abstract. Acharya SK, Dasarathy S, Tandon A, et al. Pharmacotherapeutic effects of toki-shakuyaku-san on leukorrhagia in young women. Planta Med 1983;48(5):38-42. But, she survived . Mechanisms involved in the therapeutic effects of Paeonia lactiflora Pallas in rheumatoid arthritis. Evid Based Complement Alternat Med 2016;2016:9852793. Badr, A. E., Omar, N., and Badria, F. A. Eur J Clin Pharmacol 2010;66(8):805-810. 10. View abstract. Hattori, M., Sakamoto, T., Kobashi, K., and Namba, T. Metabolism of glycyrrhizin by human intestinal flora. View abstract. View abstract. Holtmann G, Madisch A, Juergen H, et al. [Clinical study on treatment of mid-advanced crescentic nephritis by qingre huoxue recipe]. Blood Press 2009;18:192-5. Koster, M. and David, G. K. Reversible severe hypertension due to licorice ingestion. View abstract. View abstract. Strandberg TE, Andersson S, Jarvenpaa AL, et al. View abstract. Chin, Y. W., Jung, H. A., Liu, Y., Su, B. N., Castoro, J. Brouwers, A. J. and van der, Meulen J. Cureus 2020;12(11):e11656. Phytotherapy Research 1997;11:207-210. van Gelderen, C. E., Bijlsma, J. J Clin Ther Med 1999;15:499-523. Luchon, L., Meyrier, A., and Paillard, F. [Hypokalemia without arterial hypertension by licorice poisoning]. View abstract. Case Rep Emerg Med. View abstract. Z. Am J Respir.Cell Mol.Biol. Licorice is believed to have anti-androgenic effects, meaning that it may be active to reduce testosterone levels. Effect of deglycyrrhizinated liquorice on gastric mucosal damage by aspirin. Cotterill, J. Practitioner 1973;210:820-3. Botanical names: Paeonia lactiflora, Paeonia suffruticosa, Paeonia veitchii How It Works Peony contains a unique glycoside called paeoniflorin. Lorenzin, F., Degen, C., Milani, A., Siciliano, M., and Rossi, L. [Pseudo-hyperaldosteronism caused by licorice. Phytother Res 2012;26(9):1381-1384. Hawrelak, J. View abstract. View abstract. PCOS; Fertility; 25 - 45; Menopause; 45 - 60; Pregnancy Researchers from the University of Minnesota studied 50 atopic dogs in a randomized, double-blind, placebo-controlled trial. A Randomized, Double-Blind, Placebo-Controlled Clinical Trial of a Mouthwash Containing Glycyrrhiza uralensis Extract for Preventing Dental Caries. Cochrane Database Syst Rev 2004;4:CD002291. Treatment of functional dyspepsia with a herbal preparation. View abstract. Middle East J Anaesthesiol. . Sontia B, Mooney J, Gaudet L, Touyz RM. Br Med J 9-17-1977;2(6089):738-739. It might also decrease the effects of birth control pills. View abstract. Werner, S., Brismar, K., and Olsson, S. Hyperprolactinaemia and liquorice. View abstract. Papandreou V, Magiatis P, Chinou I, et al. Int Endod.J 2011;44(1):51-58. A newly-filed federal lawsuit claims eating too much of The Hershey Company's Good & Plenty and black licorice Twizzlers candies can cause serious health problems, maybe even death. Yoshida S, Takayama Y. Licorice-induced hypokalemia as a treatable cause of dropped head syndrome. The U.S. Food and Drug . Since the content of glycyrrhizin is either decreased or removed from the DGL licorice supplement, its positive effects on PCOS may also be reduced. Kimura Y, Okuda H, Okuda T, and et al. View abstract. Zhong Yao Cai 2000;23:557-60. . Some medications are changed and broken down by the liver. View abstract. No side effects or changes in liver function tests occurred during the study. Read more. Hossain, M. S., Takimoto, H., Hamano, S., Yoshida, H., Ninomiya, T., Minamishima, Y., Kimura, G., and Nomoto, K. Protective effects of hochu-ekki-to, a Chinese traditional herbal medicine against murine cytomegalovirus infection. A. and Cunliffe, W. J. Self-medication with liquorice in a patient with Addison's disease. View abstract. and Glycyrrhiza glabra L. extracts in patients with Familial Mediterranean Fever. J Clin Endocrinol Metab 2003;88:2384-92. View abstract. Phytother Res. Rosenblat, M. and Aviram, M. Paraoxonases role in the prevention of cardiovascular diseases. J Contemp Dent Pract 2010;11(1):E088-E094. An evaluation of the efficacy of licorice gargle for attenuating postoperative sore throat: a prospective, randomized, single-blind study. Armanini D, Lewicka S, Pratesi C, et al. Klin Wochenschr 1983;61:303-5. Oh, G. S., Pae, H. O., Choi, B. M., Lee, H. S., Kim, I. K., Yun, Y. G., Kim, J. D., and Chung, H. T. Penta-O-galloyl-beta-D-glucose inhibits phorbol myristate acetate-induced interleukin-8 [correction of intereukin-8] gene expression in human monocytic U937 cells through its inactivation of nuclear factor-kappaB. Neth J Med 2005;63:149-50. World J Gastroenterol 2005;11:2124-9. . I like herbal and fuit teas and a particular favourite of mine contains liquorice. 2010;16(4):216-218. View abstract. Coloclyster of Red Peony Root Granules Alleviates Moderately Severe Acute Pancreatitis: A Double-Blinded, Placebo-Controlled, Randomized Clinical Trial. Chin Med J (Engl.) A man in Massachusetts died after eating too much black licorice, which contains a compound known to be toxic in large doses, according to a new report. View abstract. Int Immunopharmacol. The treatment of human cancer with agents prepared from bovine cartilage. Effect of glycyrrhizin on viral replication and quasispecies in patients with type C chronic hepatitis. J Altern Complement Med 2000;6:557-9. Taking peony along with birth control pills might increase the risk of side effects. View abstract. Liang Xiao, Wang YZ, Jing Liu, et al. Features : Herbal Energy & Performance: Bronson's Korean Panax Ginseng provides 1000 MG per serving to naturally support energy and physical performance without any unwanted jitters. BMJ Case Rep 2012;2012. Madisch A, Holtmann G, Mayr G, et al. Lee, S. J., Lee, H. M., Ji, S. T., Lee, S. R., Mar, W., and Gho, Y. S. 1,2,3,4,6-Penta-O-galloyl-beta-D-glucose blocks endothelial cell growth and tube formation through inhibition of VEGF binding to VEGF receptor. Kraus SD, Kaminskis A. Loop diuretics can also decrease potassium levels. Monograph. Yoon JY, Cha JM, Hong SS, et al. Zhang W, Dai SM. Overview. View abstract. Hussain RM. View abstract. Schweiz Med Wochenschr 2-26-1977;107(8):276-279. Life Sci 1993;53(5):PL63-8. Assessment of the therapeutic effect of total glycosides of peony for juvenile idiopathic arthritis: a systematic review and meta-analysis. Peony-glycyrrhiza decoction for antipsychotic-related hyperprolactinemia in women with schizophrenia: a randomized controlled trial. But not everyone will have the side . Am J Psychiatry 1994;151:617-8. Armanini D, Bonanni G, Mattarello MJ, et al. Clinical reduction of S. mutans in pre-school children using a novel liquorice root extract lollipop: a pilot study. Zhongguo Zhong.Xi.Yi Jie.He.Za Zhi 2008;28(12):1090-1092. Ir J Med Sci 2016;185(4):945-7. Lozenge-induced hypermineralcorticoid state--a unique case of licorice lozenges resulting in hypertension and hypokalemia. Clin Neurol Neurosurg 2003;105:286-7.. View abstract. View abstract. J Endocrinol Invest 2003;26:646-50. Contact Dermatitis 2021;85(4):454-455. View abstract. B., and Zhang, Z. J. Ou TT, Wu CH, Hsu JD, et al. 2016 Nov;48(11):1873-1880. doi: 10.1007/s11255-016-1345-5. Cooper, H., Bhattacharya, B., Verma, V., McCulloch, A. J., Smellie, W. S., and Heald, A. H. Liquorice and soy sauce, a life-saving concoction in a patient with Addison's disease. A., van Dokkum, W., and Savelkoul, T. J. Glycyrrhizic acid: the assessment of a no effect level. Effect of glycyrrhizin on the activity of CYP3A enzyme in humans. The dogs treated with the herbal mixture saw a 37.5 percent improvement . View abstract. Effect of orally administered shao-yao-gan-cao-tang (Shakuyaku-kanzo-to) on muscle cramps in maintenance hemodialysis patients: a preliminary study. Rackova, L., Jancinova, V., Petrikova, M., Drabikova, K., Nosal, R., Stefek, M., Kostalova, D., Pronayova, N., and Kovacova, M. Mechanism of anti-inflammatory action of liquorice extract and glycyrrhizin. 1991;11(4):199-202, 195. It's not suggested to take St. John's wort if you take blood thinners. J Gastroenterol Hepatol 1999;14(11):1093-1099. Some medications are moved in and out of cells by pumps. Too much black licorice, the federal agency says, can lead to "abnormal heart rhythms, as well as high blood pressure, edema (swelling), lethargy, and congestive heart failure." . Hukkanen J, Ukkola O, Savolainen MJ. Clin Rheumatol. View abstract. An Med Interna 1995;12(1):33-35. The efficacy and safety of total glucosides of peony in the treatment of primary Sjögren's syndrome: a multi-center, randomized, double-blinded, placebo-controlled clinical trial. CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. Das SK, Das V, Gulati AK, and et al. But I didn't take it long enough to see any change. Xu Y, Li X, Chen T, et al. Ma, X. F. [Experimental and clinical studies on the treatment of pulmonary heart disease and pulmonary hypertension with Paeonia lactiflora]. Association of emblica, licorice and belides as an alternative to hydroquinone in the clinical treatment of melasma. Licorice roots can be consumed directly to get relief from cough and sore throat. 2012;18(4):534-543. J Pharm Pharmacol 2003;55:1275-82. View abstract. 2000;20(3):173-175. Chemical studies of Chinese licorice-roots. View abstract. View abstract. Qi XG. Effects of glycyrrhizin on the pharmacokinetics of nobiletin in rats and its potential mechanism. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. View abstract. Hinoshita F, Ogura Y, Suzuki Y, et al. View abstract. Pakravan F, Salehabad NH, Karimi F, Isfahani MN. Yuan, H. N., Wang, C. Y., Sze, C. W., Tong, Y., Tan, Q. R., Feng, X. J., Liu, R. M., Zhang, J. This fragrant, perennial plant -- a member of the celery family -- has smooth purplish stems and umbrella-shaped clusters of white flowers and winged fruits in July and August. A., Ziaee, A., and Samimi, R. The efficacy of licorice root extract in decreasing transaminase activities in non-alcoholic fatty liver disease: a randomized controlled clinical trial. Influence of traditional Chinese anti-inflammatory medicinal plants on leukocyte and platelet functions. View abstract. Jia, Y. Am.J Chin Med 2004;32(4):569-578. Phytother Res 2009;23(2):246-250. View abstract. Fung AY, Look PC, Chong LY, et al. Chen, M. F., Shimada, F., Kato, H., Yano, S., and Kanaoka, M. Effect of oral administration of glycyrrhizin on the pharmacokinetics of prednisolone. Strandberg TE, Jarvenpaa AL, Vanhanen H, McKeigue PM. Celik, M. M., Karakus, A., Zeren, C., Demir, M., Bayarogullari, H., Duru, M., and Al, M. Licorice induced hypokalemia, edema, and thrombocytopenia. van Rossum, T. G., Vulto, A. G., Hop, W. C., and Schalm, S. W. Pharmacokinetics of intravenous glycyrrhizin after single and multiple doses in patients with chronic hepatitis C infection. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182. Prudden JF. Wu G, Wu N, Li T, et al. Pulmonary edema following a licorice binge. B. Licorice-associated reversible cerebral vasoconstriction with PRES. J Nat Prod 1980;43(2):259-269. Z., Zhang, Y. Menati L, Khaleghinezhad K, Tadayon M, Siahpoosh A. Edelman ER, Butala NM, Avery LL, Lundquist AL, Dighe AS. View abstract. Licorice might increase blood pressure. Vestn.Dermatol.Venerol. J Altern Complement Med 2010;16(10):1065-1071. The Potential Benefits and Side Effects of the White Peony Root. Deng, Y. Y., Chen, Y. P., Wang, L., Hu, Z., Jin, Y., Shen, L., Zhu, R., and Zhong, Y. Some medications are changed and broken down by the liver. Baba, M. and Shigeta, S. Antiviral activity of glycyrrhizin against varicella-zoster virus in vitro. 2014 Jun;20(6):516-20. View abstract. View abstract. Zhongguo Zhong.Xi.Yi Jie.He.Za Zhi 2008;28(12):1121-1123. View abstract. 2014 Jun;23(3):189-92. The dose of your warfarin might need to be changed. Effects of chalcones isolated from licorice roots on leukotriene biosynthesis in human polymorphonuclear neutrophils. View abstract. Taking licorice along with "water pills" might make potassium levels drop too low. Taking licorice with paclitaxel might decrease the effects of paclitaxel. Licorice (Glycyrrhizae Radix) 15 g: NR: Zhao (2016) [36] . OTHER NAME(S): Bai Shao, Chi Shao, Chinese Peony, Common Peony, C. Peony (Paeonia lactiflora) is an herb. View abstract. 2009;14(1):64-65. View abstract. Saw palmetto might make your risk of bleeding higher if you also take a blood thinner, such as: Aspirin; Clopidogrel; Warfarin; St. John's wort. View abstract. View abstract. Akbari N, Asadimehr N, Kiani Z. 4-14-2001;145(15):744-747. therapy. Phytother Res 2008;22(2):141-148. J Altern Complement Med 2009;15(4):439-443. All rights reserved. Drug Metab Dispos 2002;30:709-15.. View abstract. Some research studies have found Angelica Sinensis to be beneficial for its effects on some symptoms of menopause. Licorice can decrease how quickly the body breaks down corticosteroids. Information from this source is evidence-based and objective, and without commercial influence. This could change the effects and side effects of these medications. Neurology 2010;75(21):1939-1941. Yamada, K., Kanba, S., Yagi, G., and Asai, M. Effectiveness of herbal medicine (shakuyaku-kanzo-to) for neuroleptic-induced hyperprolactinemia. Shen, A. Y., Wang, T. S., Huang, M. H., Liao, C. H., Chen, S. J., and Lin, C. C. Antioxidant and antiplatelet effects of dang-gui-shao-yao-san on human blood cells. Paeoniflorin: an antihyperlipidemic agent from Paeonia lactiflora. Tewari SN, Wilson AK. Saeedi, M., Morteza-Semnani, K., and Ghoreishi, M. R. The treatment of atopic dermatitis with licorice gel. View abstract. Br J Clin Pract 1972;26(12):563-566. Life Sci 2005;78:413-20 . J Ethnopharmacol 2011;135(1):162-72. G Ital Dermatol Venereol 2010;145(6):789-792. Volatiles with antimicrobial activity from the roots of Greek Paeonia taxa. Meng Xiangrui is an academic researcher. Clin Rheumatol. View abstract. Chen MF, Shimada F, Kato H, Yano S, Kanaoka M. Effect of glycyrrhizin on the pharmacokinetics of prednisolone following low dosage of prednisolone hemisuccinate. [Severe hypokalemia after holidays return]. 2020;16(3):458-462. Inflammopharmacology 2022;30(2):477-486. Peony might change how quickly the liver breaks down these medications. Some birth control pills contain estrogen. Cumming, A. M., Boddy, K., Brown, J. J., Fraser, R., Lever, A. F., Padfield, P. L., and Robertson, J. I. Efficacy and tolerability of hydroalcoholic extract of Paeonia officinalis in children with intractable epilepsy: An open-label pilot study. View abstract. View abstract. Traditional Chinese medicines Wu Wei Zi (Schisandra chinensis Baill) and Gan Cao (Glycyrrhiza uralensis Fisch) activate pregnane X receptor and increase warfarin clearance in rats. Additional reporting by Meghan De Maria. Mumoli, N. and Cei, M. Licorice-induced hypokalemia. Lee, S. J., Lee, I. S., and Mar, W. Inhibition of inducible nitric oxide synthase and cyclooxygenase-2 activity by 1,2,3,4,6-penta-O-galloyl-beta-D-glucose in murine macrophage cells. Myopathies associated with red yeast rice and liquorice: spontaneous reports from the Italian Surveillance System of Natural Health Products. J Clin Psychopharmacol 2016;36(6):572-9. J Intern Med 1999;245:307-10. Taking too much licorice can cause high blood pressure. Immunopharmacology 1999;41(3):169-181. View abstract. View abstract. View abstract. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. The licorice root derived isoflavan glabridin inhibits the activities of human cytochrome P450S 3A4, 2B6, and 2C9. Saw palmetto. Effects of mouthwash interventions on xerostomia and unstimulated whole saliva flow rate among hemodialysis patients: a randomized controlled study. Ito, M., Nakashima, H., Baba, M., Pauwels, R., De Clercq, E., Shigeta, S., and Yamamoto, N. Inhibitory effect of glycyrrhizin on the in vitro infectivity and cytopathic activity of the human immunodeficiency virus [HIV (HTLV- III/LAV)]. View abstract. Licorice is an herb that grows in parts of Europe and Asia. View abstract. View abstract. View abstract. Mol Cell Endocrinol. Phytomedicine 2003;10:271-85. A specific type of peony product, total glucosides of peony (TGP), has most often been used by adults in doses of 600 mg by mouth three times daily for up to 24 weeks. Large amounts of licorice can decrease potassium levels in the body. Armanini D, De Palo CB, Mattarello MJ, et al. In Vivo 2021;35(4):2163-2169. It combined licorice, dates, peonies, and skullcap, and was traditionally prepared as a tea. Liquorice-induced rise in blood pressure: a linear dose-response relationship. Chatterjee, N., Domoto-Reilly, K., Fecci, P. E., Schwamm, L. H., and Singhal, A. Am J Epidemiol 2002;156:803-5.. View abstract. . Severe hypokalaemia with paralysis induced by small doses of liquorice. View abstract. Glycyrrhizin, an active component of liquorice roots, and replication of SARS-associated coronavirus. Mayo Clin Proc 2003;78:767-8. Gender may affect the action of garlic oil on plasma cholesterol and glucose levels of normal subjects. View abstract. Am J Chin Med 2003;31:445-53. . View abstract. Advancing combination treatment with glycyrrhizin and boswellic acids for hospitalized patients with moderate COVID-19 infection: a randomized clinical trial. The effect of dong quai on menopausal symptoms is unknown. Side effects, toxicity, and interactions. View abstract. A., Braun, T. M., and Jacobson, J. J. Int J Environ Res Public Health 2021;19(1):242. Ruiz-Granados, E. S., Shouls, G., Sainsbury, C., and Antonios, T. A salty cause of severe hypertension. Wu, T. H., Chiu, T. Y., Tsai, J. S., Chen, C. Y., Chen, L. C., and Yang, L. L. Effectiveness of Taiwanese traditional herbal diet for pain management in terminal cancer patients. Cinatl J, Morgenstern B, Bauer G, et al. Nabeshima, S., Kashiwagi, K., Ajisaka, K., Masui, S., Takeoka, H., Ikematsu, H., and Kashiwagi, S. A randomized, controlled trial comparing traditional herbal medicine and neuraminidase inhibitors in the treatment of seasonal influenza. View abstract. Effect of Shakuyaku-kanzo-to (Tsumura TJ-68) on muscle cramps accompanying cirrhosis in a placebo-controlled double-blind parallel study. We could use compounds in these foods to . The immediate effect of Shakuyaku-kanzo-to, traditional Japanese herbal medicine, for muscular cramps during maintenance hemodialysis. Aliment Pharmacol Ther 2004;20:1279-87. Balakrishnan, V., Pillai, M. V., Raveendran, P. M., and Nair, C. S. Deglycyrrhizinated liquorice in the treatment of chronic duodenal ulcer. The effects of dietary licorice flavonoid oil supplementation on body balance control in healthy middle-aged and older Japanese women undergoing a physical exercise intervention: a randomized, double-blind, placebo-controlled trial. View abstract. Sakamoto, S., Yoshino, H., Shirahata, Y., Shimodairo, K., and Okamoto, R. Pharmacotherapeutic effects of kuei-chih-fu-ling-wan (keishi-bukuryo-gan) on human uterine myomas. Maeda T, Shinozuka K, Baba K, et al. View abstract. J Telemed Telecare. J Dermatolog Treat 2003;14(3):153-157. typica. The herb has also been studied for use in canine atopic dermatitis along with white peony (Paeonia lactiflora) and licorice (Glycyrrhiza glabra). Drugs & Vitamins . Zhang W, Leonard T, Bath-Hextall F, et al. Brush, J., Mendenhall, E., Guggenheim, A., Chan, T., Connelly, E., Soumyanath, A., Buresh, R., Barrett, R., and Zwickey, H. The effect of Echinacea purpurea, Astragalus membranaceus and Glycyrrhiza glabra on CD69 expression and immune cell activation in humans. View abstract. Licorice might decrease how well cisplatin works. View abstract. View abstract. Asian Medical Journal 1984;26(7):423-438. Effects of the Japanese herbal medicine "Sho-saiko-to" (TJ-9) on in vitro interleukin-10 production by peripheral blood mononuclear cells of patients with chronic hepatitis C. Hepatology 1997;25(6):1390-1397. Radix Paeoniae Alba increases serum estrogen level and up-regulates estrogen receptor expression in uterus and vagina of immature/ovariectomized mice. Muscle cramps.Early research suggests that taking a specific combination of peony and licorice (Shakuyaku-kanzoh-to) might ease muscle cramps in people with liver cirrhosis and in people undergoing hemodialysis. The herb licorice may lower warfarin levels and can add to digoxin's effects. View abstract. Mu Y, Zhang J, Zhang S, et al. 1. Evid Based Complement Alternat Med. Pseudohyperaldosteronism, liquorice, and hypertension. View abstract. 2017 Apr 1;27(2):150-154. doi: 10.1684/ejd.2016.2946. The glycyrrhizin and glycyrrhetic acid constituents of licorice have significant anti-androgen effects, 32-34 which may be helpful in reducing androgenic symptoms in women with PCOS. They also have a range of other intriguing activities. Because of its beneficial effects, the licorice root has been dubbed the "Medicinal plant of 2012." Now scientists have discovered that licorice root from the papilionaceae or leguminous family . Erratum in: Clin Rheumatol. Armanini D, Bonanni G, Palermo M. Reduction of serum testosterone in men by licorice. Immunology 1997;90(1):115-120. View abstract. Biofactors 2009;35(1):98-104. Wilson, J. J Nutr Sci Vitaminol.